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Pclp drug8/22/2023 ![]() ![]() Unconventional myosins modulate the spatial organization of endocytic trafficking and tether membranes or transport them along the actin cytoskeletons. Actin and unconventional myosin have crucial roles in subcellular trafficking of receptors research has also revealed a growing number of unconventional myosins that have crucial roles in TGF-β signaling. These findings originate from the pivotal function of TGF-β in development, cell proliferation, tumor metastasis, and many other processes essential in malignancy. Recent findings have revealed the role of membrane traffic in the signaling of transforming growth factor-β (TGF-β).
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